MMP Remodeling Antibody Panel
MMP Remodeling antibody panel (IR5002)
*Benefits
-Drug treatment and conditional medium for MMP Biological
Component | Clonality | Reactivity | Package |
MMP1 antibody | Rabbit pAb | Hu | 25 ul |
MMP2 antibody | Rabbit pAb | Hu, Ms, Rat | 25 ul |
MMP9 antibody | Rabbit pAb | Hu | 25 ul |
MMP14 / MT1-MMP antibody | Rabbit pAb | Hu, Ms, Rat | 25 ul |
Matrix remodeling is mainly controlled by MMPs and TIMPs. The matrix metalloproteinase (MMP) family of proteases are a group of zinc-dependent enzymes that target extracellular proteins, including growth factors, cell surface receptors, adhesion molecules, matrix structural proteins, and other proteases. Among the family members, MMP-2, MMP-3, MMP-7, MMP-9, and MMP14 (MT1-MMP) have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis, and apoptosis. MMP activity is regulated by mechanisms of both transcriptional control and post translational protein processing.