IR77-264 / IR77-263 CD45 antibody (Leukocyte Marker)
Host : Rabbit
Clonality : Polyclonal
Package : 100 μl, 25 μl
MW (kDa): 170-260
- also available conjugated to PE, FITC, HiLyte Fluor488, 647, 594, 555 for IF and FCM
Catalog | Component | Clonality | Reactivity | App |
IR77-263 | CD45 antibody (extracellular domain) | Rab-pAb | H, M | CTC / WB / FC / IF |
IR77-264 | CD45 antibody (intracellular domain) | Rab-pAb | Human | CTC / IHC / WB / FC / IF |
The protein phosphatase (PTP) receptor CD45 is a type I transmembrane protein comprised of a pair of intracellular tyrosine phosphatase domains and a variable extracellular domain generated by alternative splicing . CD45 interacts directly with antigen receptor complex proteins or activates Src family kinases involved in the regulation of T- and B-cell antigen receptor signaling. Human leukocytes including lymphocytes, eosinophils, monocytes, basophils, and neutrophils express CD45, while erythrocytes and platelets are negative for CD45 expression.