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IR77-264 / IR77-263 CD45 antibody (Leukocyte Marker)3
Home Products Primary antibody Immune Cell IR77-264 / IR77-263 CD45 antibody (Leukocyte Marker)
IR77-264

IR77-264 / IR77-263 CD45 antibody (Leukocyte Marker)

Host : Rabbit
Clonality : Polyclonal
Package : 100 μl, 25 μl
MW (kDa): 170-260

  • also available conjugated to PEFITC, HiLyte Fluor488, 647, 594, 555 for IF and FCM 

Catalog

Component

Clonality

Reactivity

App

IR77-263

CD45 antibody (extracellular domain)

Rab-pAb

H, M

CTC / WB / FC / IF

IR77-264

CD45 antibody

(intracellular domain)

Rab-pAb

Human

CTC / IHC / WB / FC / IF




The protein phosphatase (PTP) receptor CD45 is a type I transmembrane protein comprised of a pair of intracellular tyrosine phosphatase domains and a variable extracellular domain generated by alternative splicing .  CD45 interacts directly with antigen receptor complex proteins or activates Src family kinases involved in the regulation of T- and B-cell antigen receptor signaling. Human leukocytes including lymphocytes, eosinophils, monocytes, basophils, and neutrophils express CD45, while erythrocytes and platelets are negative for CD45 expression.
Immune Cell 1337005