Exosome
CD31
Antibodies Panel
IR96-401 anti-Caspase 3 p17/19 antibody WB image IR96-401 anti-Caspase 3 p17/19 antibody IHC image IR96-401 anti-Caspase 3 p17/19 antibody ICC/IF image IR96-401 anti-Caspase 3 p17/19 antibody WB image
+1
21
2
Catalog Number：IR96-401

Caspase 3 p17/19 antibody

Application
  • WB
  • IF
  • IHC
Reactivity Hu、Ms、Rat

REACTIVITYHu、Ms、Rat
SENSITIVITYEndogenous
MW35/33, 17/19
SOURCERabbit-IgG

Product Includes

-

Application Dilution

Western Blot 1:1000
Immunofluorescence 1:400 – 1:500
Immunohistochemistry (Paraffin) 1:100 – 1:300

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative

Specificity / Sensitivity

Endogenous

Source / Immunogen

Synthetic peptide / encompassing a sequence within the C-terminus region.

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]

#IR100-414
Hu
Caspase 9 cleaved Asp315 antibody
  • WB
  • IF
  • IHC
6
#IR105-435
Hu、Ms、Rat
Cytochrome C antibody
  • WB
  • IF
  • IHC
1
#IR101-421
Hu、Ms、Rat
PARP1 antibody
  • WB
  • IF
  • IHC
7
1
#IR93-389
Hu、Ms、Rat
BAX antibody
  • WB
  • IF
  • IHC
14
2
#IR94-392
Hu、Ms、Rat
BCL2 antibody
  • WB
  • IF
  • IHC
15
5
#IR99-409
Hu
Caspase-8 cleaved Asp374 antibody
  • WB
  • IF
  • IHC
9
3
#IR93-390
Hu、Ms、Rat
BAX antibody
  • WB
  • IF
  • IHC
2

Title
1

Le, Van Long et al. “Therapeutic Effects of Engineered Exosomes from RAW264.7 Cells Overexpressing hsa-let-7i-5p against Sepsis in Mice-A Comparative Study with Human Placenta-Derived Mesenchymal Stem Cell Exosomes.” Journal of personalized medicine vol. 14,6 619. 9 Jun. 2024

Application
  • WB
Reactivity Mouse
2

Chang HY, Chen JY, Ke TW, Jiang YW, Hong WZ, Tsai YY, Chiang SF, Lin YS, Huang CH, Chen TH, Chao KSC, Huang KC. Loss of MicroRNA-29b promotes DNMT3b-mediated STING downregulation to attenuate radiotherapy-induced antitumor immunity in KRAS-mutated colorectal cancer. NPJ Precis Oncol. 2026 Jan 28;10(1):93.

Application
  • WB
Reactivity Mouse
3

Chang YT, Lin IH, Shieh JJ, Lan TH, Syu JN, Huang SS, Hou PH. Harnessing pyroptosis to restrain melanoma through aripiprazole. Apoptosis. 2026 Jan 10;31(1):19.

Application
  • WB
Reactivity Human
4

Wang CH, Mai RT, Khoo KJ, Hung CF, Yang CK, Wu MJ, Chao CH. ENO2 sustains cancer stemness and metastatic competence through a phosphoenolpyruvate-dependent metabolic axis in triple-negative breast cancer. Cell Death Dis. 2026 Jul 11.

Application
  • WB
  • IHC
Reactivity Human
5

Hung MC, Chiou HL, Hsieh YH, Chen PN, Yu YL, Lee HL. Licoricidin triggers reactive oxygen species-mediated PANoptosis in human hepatocellular carcinoma cells. Int J Med Sci. 2026 Jul 13;23(8):2610-2620.

Application
  • WB
Reactivity Human
6

Ma WJ, Hung PJ, Chang FC, Leclerc M, Huang ACW. Akkermansia Muciniphila vs. Fluoxetine: Amelioration of Depression-like Behaviors and Cognitive Dysfunction Through Distinct Neurobiological Mechanisms. Probiotics Antimicrob Proteins. 2026 May;18(4):5793-5817.

Application
  • IHC
Reactivity Rat
7

Huang XF, Chang KF, Tsai NM. Inhibitory effects of patchouli alcohol on hepatocellular carcinoma growth through accumulation of oxidative stress and inactivation of androgen receptor signaling. Int J Med Sci. 2026 Feb 18;23(4):1174-1189.

Application
  • WB
Reactivity Human
8

Chien JH, Chang KF, Chen YC, Hsieh MC, Tsai NM. Anticancer effects of Commiphora myrrha extract on colorectal cancer through regulation of metastasis, cell cycle progression, and apoptosis in vitro and in vivo. Med Oncol. 2025 Nov 11;42(12):547.

Application
  • WB
Reactivity Human
9

Chen JY, Ke TW, Chiang SF, Hong WZ, Chang HY, Liang JA, Tsai YY, Huang CH, Chen WT, Chao KSC, Huang KC. CHK1 inhibition increases the therapeutic response to radiotherapy via antitumor immunity in ARID1A-deficient colorectal cancer. Cell Death Dis. 2025 Aug 1;16(1):584.

Application
  • WB
Reactivity Mouse
10

Wen ZQ, Hsu WM, Chiou CC, Maulana FA, Chang CH, Huang JM, Yu ZK, Chen CC, Lin NY, Tsai CF, Lai JS, Chen YL, Wu PY. Targeting neuroblastoma with 3β,5α-tetrahydrocorticosterone: Activation of aryl hydrocarbon receptor inhibits tumor growth, metastasis, and stemness while promoting neural differentiation. Chem Biol Interact. 2025 Nov 1;421:111780.

Application
  • WB
Reactivity Human
11

Huang, Kevin Chih-Yang et al. “TNFα modulates PANX1 activation to promote ATP release and enhance P2RX7-mediated antitumor immune responses after chemotherapy in colorectal cancer.” Cell death & disease vol. 15,1 24. 9 Jan. 2024

Application
  • WB
Reactivity Human
12

Lee, Ching-Chang et al. “Suppression of oral cancer by induction of cell cycle arrest and apoptosis using Juniperus communis extract.” Bioscience reports vol. 40,9 (2020): BSR20202083.

Application
  • WB
Reactivity Human
13

Huang, Kevin Chih-Yang et al. “Neoantigen-augmented iPSC cancer vaccine combined with radiotherapy promotes antitumor immunity in poorly immunogenic cancers.” NPJ vaccines vol. 9,1 95. 31 May. 2024

Application
  • WB
  • IHC
Reactivity Mouse
14

Chen, Jhen-Yu et al. “Activation of STING by the novel liposomal TLC388 enhances the therapeutic response to anti-PD-1 antibodies in combination with radiotherapy.” Cancer immunology, immunotherapy : CII vol. 73,5 92. 2 Apr. 2024

Application
  • WB
Reactivity Human、Mouse
15

Huang, Yu-Chen et al. “Nutraceutical Potential of Djulis (Chenopodium formosanum) Hull: Phytochemicals, Antioxidant Activity, and Liver Protection.” Antioxidants (Basel, Switzerland) vol. 13,6 721. 13 Jun. 2024

Application
  • WB
Reactivity Mouse
16

Tung, Yu-Tang et al. “Anti-Inflammatory Effects of Anthocyanin-Enriched Black Soybean Seed Coat (BSSC) Crude Extract on LPS-Induced Acute Liver Injury in Mice.” Antioxidants (Basel, Switzerland) vol. 13,3 311. 1 Mar. 2024

Application
  • WB
Reactivity Mouse
17

Wei, Po-Li et al. “PCTAIRE Protein Kinase 1 (PCTK1) Suppresses Proliferation, Stemness, and Chemoresistance in Colorectal Cancer through the BMPR1B-Smad1/5/8 Signaling Pathway.” International journal of molecular sciences vol. 24,12 10008. 11 Jun. 2023

Application
  • WB
Reactivity Human
18

Liang, Chi-Yen et al. “Patchouli alcohol induces G0 /G1 cell cycle arrest and apoptosis in vincristine-resistant non-small cell lung cancer through ROS-mediated DNA damage.” Thoracic cancer, 10.1111/1759-7714.14982. 30 May. 2023

Application
  • WB
  • ICC/IF
Reactivity Human
19

Chien, Ju-Huei et al. “Cedrol restricts the growth of colorectal cancer in vitro and in vivo by inducing cell cycle arrest and caspase-dependent apoptotic cell death.” International journal of medical sciences vol. 19,13 1953-1964. 31 Oct. 2022

Application
  • WB
Reactivity Human
20

Chang, Jui-Chih et al. “Regulation of mitochondrial fusion and mitophagy by intra-tumoral delivery of membrane-fused mitochondria or Midiv-1 enhances sensitivity to doxorubicin in triple-negative breast cancer.” Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol. 153 (2022)

Application
  • IHC
Reactivity Mice
21

Huang, Kevin Chih-Yang et al. “Engineered sTRAIL-armed MSCs overcome STING deficiency to enhance the therapeutic efficacy of radiotherapy for immune checkpoint blockade.” Cell death & disease vol. 13,7 610. 14 Jul. 2022

Application
  • WB
Reactivity Human

Reviews

Customer Feedback
2022-10-05 14:14:29
0
0
Customer Feedback
2022-10-05 14:14:29
0
0

Customer feedback Image
Application : Western blot
Condition / Dilution：1-1000, 3%BSA
Sample : HCT-116 drug treatment
Data from : Taipei Medical University
Customer Feedback
2022-10-05 14:12:43
0
0
Customer Feedback
2022-10-05 14:12:43
0
0

Customer feedback Image
Application : Western blot
Condition / Dilution： 1-1000, 3%BSA
Sample : HCT-116 drug treatment
Data from : Taipei Medical University
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