SARS-Cov-2
Apoptosis
IR188-706 anti-ERK1+ERK2 phospho (Thr202 / Tyr204) antibody WB image IR188-706 anti-ERK1+ERK2 phospho (Thr202 / Tyr204) antibody WB image
Catalog Number:IR188-706

Phospho-ERK1+ERK2 (Thr202 / Tyr204) antibody

Application
  • WB
  • IF
Reactivity Hu、Ms、Rat

REACTIVITYHu、Ms、Rat
SENSITIVITYEndogenous
MW42, 44
SOURCERabbit-IgG

Product Includes

-

Application Dilution

Western Blot 1:500-1:1000
Immunofluorescence 1:200-1:500

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative

Specificity / Sensitivity

Endogenous

Source / Immunogen

Synthetic peptide corresponding to residues surrounding Thr202 of human ERK

This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]

Title
No data.

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