Antibodies Panel
IR188-706 anti-ERK1+ERK2 phospho (Thr202 / Tyr204) antibody WB image IR188-706 anti-ERK1+ERK2 phospho (Thr202 / Tyr204) antibody WB image
Catalog Number:IR188-706

Phospho-ERK1+ERK2 (Thr202 / Tyr204) antibody

  • WB
  • IF
Reactivity Hu、Ms、Rat

MW42, 44

Product Includes


Application Dilution

Western Blot 1:500-1:1000
Immunofluorescence 1:200-1:500


Store at +4°C for short term storage. Long time storage is recommended at -20°C
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative

Specificity / Sensitivity


Source / Immunogen

Synthetic peptide corresponding to residues surrounding Thr202 of human ERK

This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]


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