SARS-Cov-2
Apoptosis
IR251-890 anti-CD8 antibody FACS image IR251-890 anti-CD8 antibody WB image
Catalog Number:IR251-890

CD8 antibody

Application
  • WB
  • IHC
  • FC
Reactivity Hu

REACTIVITYHu
SENSITIVITYEndogenous
MW36
SOURCERabbit-IgG

Product Includes

-

Application Dilution

Western Blot 1:500
Immunohistochemistry (Paraffin) 1:200 – 1:400
Flow Cytometry 1:100

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative

Specificity / Sensitivity

Endogenous

Source / Immunogen

Synthetic peptide / Extracellular domain corresponding to Human CD8

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]

Title
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