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Product Includes
Application Dilution
Flow Cytometry 1:100
Immunohistochemistry (Paraffin) 1:100 – 1:200
Storage
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
Specificity / Sensitivity
Source / Immunogen
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
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Application
Reactivity
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Application
Reactivity Rat
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Reviews
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Application : Aggregation
Sample : Exosome rich PBMC
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Application : Western blot
Condition : 10% gel, Protein loading: 20 µg
Loading volume: 15 µl, Transfer 1.5 hr
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Dilution : 1-1000
Sample : Human TNBC plasma_Triple-negative breast cancer
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Dilution : 1-1000
Sample : Human Breast Cancer Buffy coat