CD4 (mouse specific), [RM4-5] monoclonal antibody
Product Includes
Application Dilution
Flow Cytometry 1:50-1:100
Storage
Phosphate-buffered solution, pH 7.2, containing 0.025% ProClin 300 , 20% Glycerol.
Specificity / Sensitivity
Source / Immunogen
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
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Reviews
IRR002 anti-CD4 antibody ICC image
Immunofluorescence: cells were fixed with 4% paraformaldehyde for 10 min at RT, permeabilized with 0.1% NP-40 for 10 min at RT then blocked with 5% BSA for 30 min at room temperature. Cells were stained with IRR002 anti- CD4 antibody (red) at 1:200 and 4°C. DAPI (blue) was used as the nuclear counter stain.
IRR002 anti-CD4 antibody FACS image
Product：CD4 antibody
Catalog：IRR002
Sample : C57BL/6 mouse splenocytes