SARS-Cov-2
Apoptosis
IRM010 anti-STAT5 monoclonal antibody WB image IRM010 anti-STAT5 monoclonal antibody IHC image IRM010 anti-STAT5 monoclonal antibody ICC/IF image
Catalog Number:IRM010

STAT5 , monoclonal antibody

Application
  • WB
  • IF
  • IHC
Reactivity Hu、Ms、Rat

REACTIVITYHu、Ms、Rat
SENSITIVITYEndogenous
MW90-95
SOURCEMouse IgG1

Product Includes

-

Application Dilution

Western Blot 1:500-1:1000
Immunofluorescence 1:100-1:200
Immunohistochemistry (Paraffin) 1:50-1:100

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C
Phosphate buffered solution, pH 7.2, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative

Specificity / Sensitivity

Endogenous

Source / Immunogen

-

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]

Title
No data.

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