Catalog Number:IR218-1-Bio
EpCAM antibody Biotinylated (Intracellular domain)
Application
Reactivity Hu、Ms、Rat
| REACTIVITY | Hu、Ms、Rat |
|---|---|
| SENSITIVITY | Endogenous |
| MW | 34-40 |
| SOURCE | Rabbit-IgG |
Product Includes
-
Application Dilution
Western Blot 1:1000 – 1:2000
Immunofluorescence 1:200 – 1:400
CTC Reported in the literature, not verified in house.
Immunofluorescence 1:200 – 1:400
CTC Reported in the literature, not verified in house.
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
Specificity / Sensitivity
Endogenous
Source / Immunogen
Synthetic peptide / Intracellular domain corresponding to Human EpCAM
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
