Antibodies Panel
IR112-457 anti TGF beta 1 antibody WB image IR112-457 anti TGF beta 1 antibody WB image IR112-457 anti TGF beta 1 antibody WB image IR112-457 anti TGF beta 1 antibody ICC/IF image
Catalog Number:IR112-457

TGF beta 1 antibody

  • WB
  • IF
  • IHC
Reactivity Hu、Ms、Rat

MW12, 33-60

Product Includes


Application Dilution

Western Blot 1:500
Immunofluorescence 1:100–1:200
Immunohistochemistry (Paraffin) 1:50–1:100


Store at +4°C for short term storage. Long time storage is recommended at -20°C
100mM Tris Glycine, 1% BSA, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative

Specificity / Sensitivity


Source / Immunogen

Synthetic peptide / encompassing a sequence within the C-terminus region.

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016]

No data.


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