SARS-Cov-2
Apoptosis
IRM208 HSP27 antibody [6D9] WB image IRM208 HSP27 antibody [6D9] ICC/IF image
Catalog Number:IRM208

HSP27 antibody [6D9]

Application
  • WB
  • IF
Reactivity Hu

REACTIVITYHu
SENSITIVITYEndogenous
MW27
SOURCEmouse IgG1

Product Includes

-

Application Dilution

Western Blot 1:1000-1:2000
Immunofluorescence 1:200 – 1:500

Storage

Long time storage is recommended at -20°C
Phosphate-buffered solutions, pH 7.2, 50% Glycerol, 0.025% ProClin 300 was added as a preservative
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

Specificity / Sensitivity

Endogenous

Source / Immunogen

-

This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. [provided by RefSeq, Aug 2017]

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