

Catalog Number:IR30-78
CD133 / Prominin-1 antibody (Extracellular domain)
Application
Reactivity Hu
Product Includes
-
Application Dilution
Western Blot Assay-dependent
Immunofluorescence 1: 200
Immunohistochemistry (Paraffin) 1:100
Immunofluorescence 1: 200
Immunohistochemistry (Paraffin) 1:100
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
Specificity / Sensitivity
Endogenous
Source / Immunogen
Synthetic peptide / Intracellular domain corresponding to Human CD133.
This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]