Exosome
CD31
Antibodies Panel
IR2-7 anti-Beta Actin antibody WB image IR2-7 anti-Beta Actin antibody IHC image IR2-7 anti-Beta Actin antibody IHC image IR2-7 anti-Beta Actin antibody_MDA-MB-231 ICC/IF image
+3
12
Catalog Number:IR2-7

Beta Actin antibody

Application
  • WB
  • IF
  • IHC
Reactivity Hu、Ms、Rat

REACTIVITYHu、Ms、Rat
SENSITIVITYEndogenous
MW43
SOURCERabbit-IgG

Product Includes

-

Application Dilution

Western Blot 1:2000-1:5000
Immunofluorescence 1:600-1:700
Immunohistochemistry (Paraffin) 1:400-1:600

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C
100mM Tris Glycine, 1% BSA, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative

Specificity / Sensitivity

Endogenous

Source / Immunogen

Synthetic peptide / encompassing a sequence within the C-terminus region.

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause a variety of myopathies, including nemaline myopathy, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects with manifestations such as hypotonia. [provided by RefSeq, Sep 2019]

Title
1

Chang, Kai-Fu et al. “Cedrol, a Sesquiterpene Alcohol, Enhances the Anticancer Efficacy of Temozolomide in Attenuating Drug Resistance via Regulation of the DNA Damage Response and MGMT Expression.” Journal of natural products vol. 83,10 (2020): 3021-3029.

Application
  • WB
Reactivity Human
2

Chien, Ju-Huei et al. “Extract of Pogostemon cablin Possesses Potent Anticancer Activity against Colorectal Cancer Cells In Vitro and In Vivo.” Evidence-based complementary and alternative medicine : eCAM vol. 2020 9758156. 9 Sep. 2020

Application
  • WB
Reactivity Mouse
3

Hung, Pei-Hsiu et al. “Effects of Cedrus atlantica extract on acute myeloid leukemia cell cycle distribution and apoptosis.” Molecular biology reports vol. 47,11 (2020): 8935-8947.

Application
  • WB
Reactivity Human
4

Li, Chia-Yu et al. “Cell cycle arrest and apoptosis induction by Juniperus communis extract in esophageal squamous cell carcinoma through activation of p53-induced apoptosis pathway.” Food science & nutrition vol. 9,2 1088-1098. 30 Dec. 2020

Application
  • WB
Reactivity Human
5

Chang, Kai-Fu et al. “Positively Charged Nanoparticle Delivery of n-Butylidenephthalide Enhances Antitumor Effect in Hepatocellular Carcinoma.” BioMed research international vol. 2021 8817875. 19 Mar. 2021

Application
  • WB
Reactivity Human、Mouse
6

Lai, Wen-Lin et al. “Juniperus communis extract induces cell cycle arrest and apoptosis of colorectal adenocarcinoma in vitro and in vivo.” Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas vol. 54,10 e10891. 16 Jul. 2021

Application
  • WB
Reactivity Human、Mouse
7

Chang, Kai-Fu et al. “Cedrus atlantica Extract Suppress Glioblastoma Growth through Promotion of Genotoxicity and Apoptosis: In Vitro and In Vivo Studies.” International journal of medical sciences vol. 18,11 2417-2430. 22 Apr. 2021

Application
  • WB
Reactivity Human、Mouse
8

Chien, Ju-Huei et al. “Cedrol restricts the growth of colorectal cancer in vitro and in vivo by inducing cell cycle arrest and caspase-dependent apoptotic cell death.” International journal of medical sciences vol. 19,13 1953-1964. 31 Oct. 2022

Application
  • WB
Reactivity Human
9

Huang, Chih-Yuan et al. “Cedrus atlantica extract exerts antiproliferative effect on colorectal cancer through the induction of cell cycle arrest and apoptosis.” Food science & nutrition vol. 10,5 1638-1648. 21 Feb. 2022

Application
  • WB
Reactivity Human
10

Liang, Chi-Yen et al. “Patchouli alcohol induces G0 /G1 cell cycle arrest and apoptosis in vincristine-resistant non-small cell lung cancer through ROS-mediated DNA damage.” Thoracic cancer, 10.1111/1759-7714.14982. 30 May. 2023

Application
  • WB
  • ICC/IF
Reactivity Human
11

Chang, Kai-Fu et al. “Downregulation of VEGFR2 signaling by cedrol abrogates VEGF‑driven angiogenesis and proliferation of glioblastoma cells through AKT/P70S6K and MAPK/ERK1/2 pathways.” Oncology letters vol. 26,2 342. 22 Jun. 2023

Application
  • WB
Reactivity Human
12

Cho, Shu-Chi, and Shyh-Yu Shaw. “Tea seed saponin‑reduced extract ameliorates palmitic acid‑induced insulin resistance in HepG2 cells.” Molecular medicine reports vol. 29,2 (2024)

Application
  • WB
Reactivity Human

Reviews

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