Exosome
CD31
Antibodies Panel
IR299-1 anti-Phospho-Troponin I (Cardiac) (Ser23/24) antibody WB image
Catalog Number:IR299-1

Phospho-Troponin I (Cardiac) (Ser23/24) antibody

Application
  • WB
  • IF
Reactivity Hu、Ms、Rat

REACTIVITYHu、Ms、Rat
SENSITIVITYEndogenous
MW28
SOURCERabbit-IgG

Product Includes

-

Application Dilution

Western Blot 1:1000 – 1:2000
Immunofluorescence 1:200 – 1:400

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.
100mM Tris Glycine, 30% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

Specificity / Sensitivity

Endogenous

Source / Immunogen

Synthetic peptide corresponding to residues surrounding Ser23/24 of human Troponin I (Cardiac)

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Troponin I is useful in making a diagnosis of heart failure, and of ischemic heart disease. An elevated level of troponin is also now used as indicator of acute myocardial injury in patients hospitalized with moderate/severe Coronavirus Disease 2019 (COVID-19). Such elevation has also been associated with higher risk of mortality in cardiovascular disease patients hospitalized due to COVID-19. [provided by RefSeq, Aug 2020]



Title
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