| REACTIVITY | Hu、Ms、Rat |
|---|---|
| SENSITIVITY | Endogenous |
| MW | 175 |
| SOURCE | Rabbit-IgG |
Product Includes
Application Dilution
Immunofluorescence 1:200 – 1:400
Storage
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Specificity / Sensitivity
Source / Immunogen
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020]
IR280-2 anti-Phospho-EGFR (Tyr1068) antibody WB image
Anti-Phospho-EGFR (Tyr1068) antibody at 1/1000 dilution
Lysates/proteins at 20 μg per lane
This blot was produced using a 5% SDS-PAGE. Nitrocellulose membrane was then blocked for an hour before being incubated with IR280-2 overnight at 4°C.
Dot blot for specificity and sensitivity of Phospho-EGFR (Tyr1068) Antibody (IR280-2).