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IR43-128 anti-alpha Synuclein antibody WB image Customer feedback Image IR43-128 anti-alpha Synuclein antibody IF image Customer feedback Image IR43-128 anti-alpha Synuclein antibody IHC image IR43-128 anti-alpha Synuclein antibody ICC/IF image
Catalog Number:IR43-128

alpha Synuclein / SNCA antibody

Application
  • WB
  • IF
  • IHC
Reactivity Hu、Ms、Rat

REACTIVITYHu、Ms、Rat
SENSITIVITYEndogenous
MW15
SOURCERabbit-IgG

Product Includes

-

Application Dilution

Western Blot 1:500-1:1000
Immunofluorescence 1:200-1:300
Immunohistochemistry (Frozen) 1:100-1:200

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative

Specificity / Sensitivity

Endogenous

Source / Immunogen

Synthetic peptide / encompassing a sequence within the C-terminus region.

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]

Title
No data.

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