SARS-Cov-2
Apoptosis
IR77-264 anti-CD45 antibody WB image IR77-264 anti-CD45 antibody FACS image IR77-264 anti- CD45 antibody_Colorectal carcinoma IHC image IR77-264 anti-CD45 antibody_THP-1 ICC/IF image
+9
Catalog Number:IR77-264

CD45 antibody (Intracellular domain)

Application
  • WB
  • IF
  • IHC
  • FC
  • Pathology
Reactivity Human

REACTIVITYHuman
SENSITIVITYEndogenous
MW170 to 280
SOURCERabbit-IgG

Product Includes

-

Application Dilution

Western Blot 1:500-1:1000
Immunofluorescence 1:200-1:500
Immunohistochemistry (Paraffin) 1: 200-1:400
Flow Cytometry 1:50-1:100

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative

Specificity / Sensitivity

Endogenous

Source / Immunogen

Synthetic peptide / Intracellular domain corresponding to Human CD45

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

Title
No data.

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