CD31 as a marker for endothelial cells
CD31 or Platelet/endothelial cell adhesion molecule-1 (PECAM-1) is a 130-kDa cell adhesion molecule that is highly expressed on the surface of endothelial cells and to a lesser extent on a range of hematopoietic cells, such as platelets, monocytes, neutrophils and T-cell subsets. At endothelial cell-cell borders, CD31 forms homophilic interactions and functions as a regulator of both the vascular permeability barrier and of leukocyte trafficking (reviewed in Lertkiatmongkol et al., 2016).
| Product Name | Cat No. | Reactivity | Type | Epitope | Application |
|---|---|---|---|---|---|
| Mouse CD31 antibody | IR75-253 | Mouse | Rabbit pAb | Cell surface | WB, ICC/IF, IHC, Flow |
| CD31 antibody | IR75-254 | Human | Rabbit pAb | Cell surface | WB, ICC/IF, IHC, Flow |
IHC: CD31 staining of FFPE and Forzen
Performance in Western Blot
anti-CD31 antibodies were tested in Western Blotapplication on mouse/human tissue and cell lysate.
Literature：
Lertkiatmongkol et al., 2016. Endothelial functions of platelet/endothelial cell adhesion molecule-1 (CD31). PMID: 27055047