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Catalog Number:IR240-864
CD206 / MRC1 / Mannose Receptor antibody
Application
Reactivity Hu、Ms、Rat
Product Includes
-
Application Dilution
Western Blot 1:1000
Immunofluorescence 1:200–1:300
Immunohistochemistry 1:100-1:200
Immunofluorescence 1:200–1:300
Immunohistochemistry 1:100-1:200
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
Specificity / Sensitivity
Endogenous
Source / Immunogen
Synthetic peptide / Intracellular domain corresponding to Human CD206
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]