SARS-Cov-2
Apoptosis
IR257-912 anti-CD11b / ITGAM antibody  IHC-P image IR257-912 anti-CD11b / ITGAM antibody  IHC-P image IR257-912 anti-CD11b / ITGAM antibody WB image IR257-912 anti-CD11b / ITGAM antibody IHC-Fr image
Catalog Number:IR257-912

CD11b / ITGAM (human specific) antibody

Application
  • WB
  • IF
  • IHC
Reactivity Hu

Product Includes

-

Application Dilution

Western Blot 1:500 - 1:1000
Immunofluorescence 1:200 – 1:300
Immunohistochemistry 1: 100

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative

Specificity / Sensitivity

Endogenous

Source / Immunogen

Synthetic peptide / Extracellular domain corresponding to Human CD11b

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Title
No data.

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