Antibodies Panel
IR114-473 anti-IL1 beta antibody WB image IR114-473 anti-IL1 beta antibody IHC image IR114-473 anti-IL1 beta antibody IHC image IR114-473 anti-IL1 beta antibody IHC image
Catalog Number:IR114-473

IL1 beta antibody

  • WB
  • IF
  • IHC
Reactivity Hu、Ms、Rat

MW35, 18

Product Includes


Application Dilution

Western Blot 1:500-1:1000
Immunofluorescence 1:200-1:500
Immunohistochemistry (Paraffin) 1:100-1:300


Store at +4°C for short term storage. Long time storage is recommended at -20°C
100mM Tris Glycine,1% BSA, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative

Specificity / Sensitivity


Source / Immunogen

Synthetic peptide / encompassing a sequence within the C-terminus region.

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. Similarly, IL-1B has been implicated in human osteoarthritis pathogenesis. Patients with severe Coronavirus Disease 2019 (COVID-19) present elevated levels of pro-inflammatory cytokines such as IL-1B in bronchial alveolar lavage fluid samples. The lung damage induced by the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is to a large extent, a result of the inflammatory response promoted by cytokines such as IL-1B. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2020]

No data.


Customer Feedback
2022-11-17 10:01:27
Customer Feedback
2022-11-17 10:01:27

Customer feedback Image
Application : Western blot
Condition / Dilution: 1-500, PVDF 3%BSA
Sample : Caco-2 Treatment: 50ng/mLTNF-alpha
Data from : Taipei Medical University

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