Exosome
CD31
Antibodies Panel
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2022-11-08 16:42

Antibodies for Exosome research

Choose iReal’s Gold-Class validated antibodies for detection of exosome markers

Exosomes are small vesicles composed of a lipid bilayer. Exosomes are present in body fluids such as blood, urine, saliva, amniotic fluid, and malignant ascites. Exosomes play important roles in processes like coagulation, waste management, and intercellular signaling. They are also of interest for clinical applications such as therapy, prognosis, and markers for disease.

iReal’s Gold-Class validated antibodies against common (CD9, CD63, CD81, ALIX, Flotillin-1) and disease-specific (cancer and neurodegenerative diseases) exosomal markers. 


Featured Exosome Markers

1. Cited and independently reviewed
2. Validated using clinical sample
3. Multiple applications and species

WB Applications
Quality exosomal marker antibodies are 

validated with clinical sample for your research needs.


Highlighted Products

Exosome Antibodies

Catalog

Component

Clonality

Reactivity

App

IR300-981

 CD9 antibody

Rab-pAb

H, M, R

WB, IF, IHC

IR301-983

 CD63 antibody

Rab-pAb

H, M, R

WB, IF, IHC, Flow

IR303-988

 ALIX antibody

Rab-pAb

H, M, R

WB, IF, IHC

IR302-986

 CD81 antibody

Rab-pAb

H, M, R

WB, IF, IHC

IR304-990

Flotillin-1 antibody

Rab-pAb

New Antibodies In Development


General Exosome Markers: Tetraspanins

Markers

Function

CD9

CD81

CD63

Associate with adhesion molecules, transmembrane receptors and intracellular signaling proteins.

General Exosome Markers: Tetraspanins


General Exosome Markers: Multivesicular Body (MVB)-
Associated Proteins
Markers Function
TSG101

Interact with proteins of the midbody

Flotillin-1
Scaffolding protein within caveolar membranes

IR303-988 anti-ALIX antibody IHCand WB image

Tissue/Cell Type-Specific Exosome Markers

Cell Type Exosome Marker
Epithelial Cells
Lymphocytes
Mesenchymal
Stem/Stromal Cell (MSCs)
Platelets
Neurons L1CAM
NF-L
IR218-3 anti-EpCAM antibody WB image, IR252-1 anti-CD3 antibody_mouse spleen IHC image
IR75-257 anti-CD31/PECAM1 antibody IHC image
IR208-752 anti-CD44 antibody IHC image

Markers of Exosome Function

Cell Type Exosome Marker
Signaling
Metabolic Enzymes
Immunomodulatory
IR3-8 anti-GAPDH antibody WB image
IR108-442 anti-VEGF antibody_Colorectal carcinoma IHC image
IR49-149 anti-Beta Catenin antibody_IF_Customer feedback
IR113-466 anti-HIF1 alpha antibody IHC image

References:

  1. Cell. 2019 Apr 4;177(2):414-427.e13.
  2. Cancer Res. 2017 Dec 1;77(23):6480-6488.
  3. Nat Med. 2001 Mar;7(3):297-303.